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1

Patient Blood Management

Mueller, Markus M., Van Remoortel, Hans, Meybohm, Patrick, Aranko, Kari, Aubron, Cécile, Burger, Reinhard, Carson, Jeffrey L., Cichutek, Klaus, De Buck, Emmy, Devine, Dana, Fergusson, Dean, Folléa, Gi

Journal:

Year:

2019

Language:

english

File:

PDF, 357 KB

english, 2019

2

Klinische Anwendung der Gentherapie. Bisherige Erfahrungen und Zukunft

Dr. Barbara Langer, Prof. Dr. Klaus Cichutek

Journal:

Pharmazie in unserer Zeit

Year:

2011

Language:

german

File:

PDF, 559 KB

german, 2011

3

Trends in der Impfstoffentwicklung. DNA- und zellbasierte Impfstoffe

Jürgen Scherer, Thomas Hinz, Klaus Cichutek

Journal:

Pharmazie in unserer Zeit

Year:

2008

Language:

german

File:

PDF, 436 KB

german, 2008

4

Retroviral Vectors

M. Schweizer, E. Flory, C. J. Buchholz, K. Cichutek

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2001

Language:

english

File:

PDF, 207 KB

english, 2001

5

Gentherapie: Gut' Ding will Weile haben

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2001

Language:

german

File:

PDF, 65 KB

german, 2001

6

Suppressing active replication of a live attenuated simian immunodeficiency virus vaccine does not abrogate protection from challenge

Gabriel, Benjamin, Fiebig, Uwe, Hohn, Oliver, Plesker, Roland, Coulibaly, Cheick, Cichutek, Klaus, Mühlebach, Michael D., Bannert, Norbert, Kurth, Reinhard, Norley, Stephen

Journal:

Year:

2016

Language:

english

File:

PDF, 2.07 MB

english, 2016

7

Gene therapy in germany and in europe: regulatory issues

Klaus Cichutek, Ines Krämer

Journal:

The Quality Assurance Journal

Year:

1997

Language:

english

File:

PDF, 189 KB

english, 1997

8

Entwicklung und regulatorische Aspekte der Gentransferarzneimittel

Journal:

Chemie Ingenieur Technik

Year:

2002

File:

PDF, 42 KB

2002

9

Functional HIV-2- and SIVsmmPBj- derived lentiviral vectors generated by a novel polymerase chain reaction-based approach

Björn-Philipp Kloke, Silke Schüle, Michael D. Mühlebach, Nina Wolfrum, Klaus Cichutek, Matthias Schweizer

Journal:

The Journal of Gene Medicine

Year:

2010

Language:

english

File:

PDF, 212 KB

english, 2010

10

Is it going to be SIN? : A European Society of Gene Therapy commentary. Phasing-out the clinical use of non self-inactivating murine leukemia virus vectors: initiative on hold

Christian J. Buchholz, Klaus Cichutek

Journal:

The Journal of Gene Medicine

Year:

2006

Language:

english

File:

PDF, 52 KB

english, 2006

11

Integrated inline filtration: A method to produce highly concentrated retroviral vector titer supernatant

Dirk Nehring, Ralf Poertner, Matthias Schweizer, Klaus Cichutek, Peter Czermak

Journal:

Year:

2009

Language:

english

File:

PDF, 389 KB

english, 2009

12

Gene and Cell Therapy in Germany and the EU

Journal:

Journal für Verbraucherschutz und Lebensmittelsicherheit

Year:

2008

Language:

english

File:

PDF, 589 KB

english, 2008

13

Regulatorische Aspekte der Anwendung von Gentransfer-Arzneimitteln in der Humanmedizin

K. Cichutek, M. Schweizer, E. Flory, C. J. Buchholz

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2001

Language:

german

File:

PDF, 150 KB

german, 2001

14

Regulatorische Aspekte der Anwendung humaner Stammzellen

K. Cichutek, E. Flory, R. Seitz, M. Heiden

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2002

Language:

german

File:

PDF, 129 KB

german, 2002

15

Das Deutsche Register für somatische Gentransferstudien—DeReG

G. Dreier, K. Cichutek

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2004

Language:

german

File:

PDF, 246 KB

german, 2004

16

Neue Regeln für die Genehmigung klinischer Prüfungen in Deutschland

K. Cichutek, M. Holz-Slomczyk

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2005

Language:

german

File:

PDF, 421 KB

german, 2005

17

Genehmigung der klinischen Prüfung immunbiologischer Arzneimittel am Paul-Ehrlich-Institut

H. Krafft, K. Cichutek

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2005

Language:

german

File:

PDF, 739 KB

german, 2005

18

Grundlagen der klinischen Prüfung von Arzneimitteln

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2005

Language:

german

File:

PDF, 403 KB

german, 2005

19

Transduction efficiency of MLV but not of HIV-1 vectors is pseudotype dependent on human primary T lymphocytes

MichaelD. Mühlebach, Isabel Schmitt, Stefanie Steidl, Jörn Stitz, Matthias Schweizer, Thomas Blankenstein, Klaus Cichutek, Wolfgang Uckert

Journal:

Journal of Molecular Medicine

Year:

2003

Language:

english

File:

PDF, 452 KB

english, 2003

20

Arzneimittelrechtliche Anforderungen an Arzneimittel für neuartige Therapien aus humanen Pankreata

Jana Straßburger, Rainer Meilicke, Klaus Cichutek

Journal:

Year:

2010

Language:

german

File:

PDF, 876 KB

german, 2010

21

Comparative Analysis of Transduced Primary Human Dendritic Cells Generated by the Use of Three Different Lentiviral Vector Systems

Elena Grabski, Zoe Waibler, Silke Schüle, Björn-Philipp Kloke, Linda Y. Sender, Sylvia Panitz, Klaus Cichutek, Matthias Schweizer, Ulrich Kalinke

Journal:

Molecular Biotechnology

Year:

2011

Language:

english

File:

PDF, 455 KB

english, 2011

22

Regulatorische Anforderungen an Arzneimittel für neuartige Therapien

Bettina Klug, Jens Reinhardt, Matthias Renner, Hartmut Krafft, Klaus Cichutek

Journal:

Year:

2009

Language:

german

File:

PDF, 199 KB

german, 2009

23

SIV grows unchanged in human cells

WERNER, ALBRECHT, BAIER, MICHAEL, CICHUTEK, KLAUS, KURTH, REINHARD, BECKER, WALLY

Journal:

Year:

1990

File:

PDF, 466 KB

1990

24

Spleen necrosis virus-derived C-type retroviral vectors for gene transfer to quiescent cells

Parveen, Zahida, Krupetsky, Anna, Engelstädter, Martin, Cichutek, Klaus, Pomerantz, Roger J., Dornburg, Ralph

Journal:

Nature Biotechnology

Year:

2000

Language:

english

File:

PDF, 358 KB

english, 2000

25

Pseudotyping lentiviral vectors with the wild-type measles virus glycoproteins improves titer and selectivity

Funke, S, Schneider, I C, Glaser, S, Mühlebach, M D, Moritz, T, Cattaneo, R, Cichutek, K, Buchholz, C J

Journal:

Year:

2009

Language:

english

File:

PDF, 397 KB

english, 2009

26

Cell entry targeting restricts biodistribution of replication-competent retroviruses to tumour tissue

Duerner, L J, Schwantes, A, Schneider, I C, Cichutek, K, Buchholz, C J

Journal:

Year:

2008

Language:

english

File:

PDF, 276 KB

english, 2008

27

RNAi-mediated gene silencing in tumour tissue using replication-competent retroviral vectors

Schaser, T, Wrede, C, Duerner, L, Sliva, K, Cichutek, K, Schnierle, B, Buchholz, C J

Journal:

Year:

2011

Language:

english

File:

PDF, 535 KB

english, 2011

28

European regulation tackles tissue engineering

Sanzenbacher, Ralf, Dwenger, Anne, Schuessler-Lenz, Martina, Cichutek, Klaus, Flory, Egbert

Journal:

Nature Biotechnology

Year:

2007

Language:

english

File:

PDF, 292 KB

english, 2007

29

Replicating retroviral vectors mediating continuous production and secretion of therapeutic gene products from cancer cells

Finger, Carsten, Sun, Yuansheng, Sanz, Laura, Alvarez-Vallina, Luis, Buchholz, Christian J, Cichutek, Klaus

Journal:

Cancer Gene Therapy

Year:

2005

Language:

english

File:

PDF, 378 KB

english, 2005

30

Chronic gene delivery of interferon-inducible protein 10 through replication-competent retrovirus vectors suppresses tumor growth

Sun, Yuansheng, Finger, Carsten, Alvarez-Vallina, Luis, Cichutek, Klaus, Buchholz, Christian J

Journal:

Cancer Gene Therapy

Year:

2005

Language:

english

File:

PDF, 460 KB

english, 2005

31

Targeted gene transfer to lymphocytes using murine leukaemia virus vectors pseudotyped with spleen necrosis virus envelope proteins

Engelstädter, M, Buchholz, C J, Bobkova, M, Steidl, S, Merget-Millitzer, H, Willemsen, R A, Stitz, J, Cichutek, K

Journal:

Year:

2001

Language:

english

File:

PDF, 128 KB

english, 2001

32

Directed evolution of retroviruses activatable by tumour-associated matrix metalloproteases

Schneider, R M, Medvedovska, Y, Hartl, I, Voelker, B, Chadwick, M P, Russell, S J, Cichutek, K, Buchholz, C J

Journal:

Year:

2003

Language:

english

File:

PDF, 313 KB

english, 2003

33

An inducible T7 RNA polymerase-dependent plasmid system for the expression of short hairpin RNAs

Matthias Hamdorf, Heide Muckenfuss, Ulrich Tschulena, Stephan Pleschka, Ralf Sanzenbacher, Klaus Cichutek, Egbert Flory

Journal:

Molecular Biotechnology

Year:

2006

Language:

english

File:

PDF, 259 KB

english, 2006

34

Entwicklung eines Produktionsprozesses zur Herstellung von Masernviren für die Krebstherapie

K. Weiss, Dr. D. Salzig, Dr. M. D. Mühlebach, Prof. K. Cichutek, Prof. R. Pörtner, Prof. P. Czermak

Journal:

Chemie Ingenieur Technik

Year:

2012

Language:

german

File:

PDF, 39 KB

german, 2012

35

Self-Limiting Infection by int/nef-Double Mutants of Simian Immunodeficiency Virus

Martina Vogel, Klaus Cichutek, Steve Norley, Reinhard Kurth

Journal:

Year:

1993

File:

PDF, 736 KB

1993

36

MLV-Derived Retroviral Vectors Selective for CD4-Expressing Cells and Resistant to Neutralization by Sera from HIV-Infected Patients

Jörn Stitz, Stefanie Steidl, Heike Merget-Millitzer, Renate König, Peter Müller, Frank Nocken, Martin Engelstädter, Maria Bobkova, Isabel Schmitt, Reinhard Kurth, Christian J. Buchholz, Klaus Cichutek

Journal:

Year:

2000

Language:

english

File:

PDF, 157 KB

english, 2000

37

Lentiviral Vectors Pseudotyped with Envelope Glycoproteins Derived from Gibbon Ape Leukemia Virus and Murine Leukemia Virus 10A1

J. Stitz, C.J. Buchholz, M. Engelstädter, W. Uckert, U. Bloemer, I. Schmitt, K. Cichutek

Journal:

Year:

2000

Language:

english

File:

PDF, 300 KB

english, 2000

38

A Novel Lentivirus Vector Derived from Apathogenic Simian Immunodeficiency Virus

J. Stitz, M.D. Mühlebach, U. Blömer, M. Scherr, M. Selbert, P. Wehner, S. Steidl, I. Schmitt, R. König, M. Schweizer, K. Cichutek

Journal:

Year:

2001

Language:

english

File:

PDF, 328 KB

english, 2001

39

Coreceptor Switch of [MLV(SIVagm)] Pseudotype Vectors by V3-Loop Exchange

Stefanie Steidl, Jörn Stitz, Isabel Schmitt, Renate König, Egbert Flory, Matthias Schweizer, Klaus Cichutek

Journal:

Year:

2002

Language:

english

File:

PDF, 360 KB

english, 2002

40

Displaying Epidermal Growth Factor on Spleen Necrosis Virus-Derived Targeting Vectors

Christoph A. Merten, Martin Engelstaedter, Christian J. Buchholz, Klaus Cichutek

Journal:

Year:

2003

Language:

english

File:

PDF, 265 KB

english, 2003

41

The different iron binding sites of bovine spleen purple acid phosphatase

Klaus Cichutek, Herbert Witzel, Fritz Parak

Journal:

Hyperfine Interactions

Year:

1988

Language:

english

File:

PDF, 143 KB

english, 1988

42

Risk assessment of retroviral gene transfer during gene therapy and nucleic acid vaccination

S. Wagener, I. Treinies, R. Kurth, K. Cichutek

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1995

Language:

english

File:

PDF, 131 KB

english, 1995

43

Complete nucleotide sequence of a simian immunodeficiency virus from African green monkeys: A novel type of intragroup divergence

M. Baier, C. Garber, C. Moller, K. Cichutek, R. Kurth

Journal:

Year:

1990

Language:

english

File:

PDF, 713 KB

english, 1990

44

Lentiviral vectors with measles virus glycoproteins – dream team for gene transfer?

Christian J. Buchholz, Michael D. Mühlebach, Klaus Cichutek

Journal:

Trends in Biotechnology

Year:

2009

Language:

english

File:

PDF, 443 KB

english, 2009

45

Selective gene transfer to T lymphocytes using coreceptor-specific [MLV(HIV)] pseudotype vectors in a transgenic mouse model

Silke Schüle, Stefanie Steidl, Sylvia Panitz, Cheick Coulibaly, Ulrich Kalinke, Klaus Cichutek, Matthias Schweizer

Journal:

Year:

2006

Language:

english

File:

PDF, 828 KB

english, 2006

46

Impact of viral accessory proteins of SIVsmmPBj on early steps of infection of quiescent cells

Nina Wolfrum, Michael D. Mühlebach, Silke Schüle, Julia K. Kaiser, Björn-Philipp Kloke, Klaus Cichutek, Matthias Schweizer

Journal:

Year:

2007

Language:

english

File:

PDF, 769 KB

english, 2007

47

SIVagm containing the SHIV89.6P Envelope gene replicates poorly and is non-pathogenic

Mario Perković, Stephen Norley, Ralf Sanzenbacher, Marion Battenberg, Sylvia Panitz, Cheik Coulibaly, Egbert Flory, Christine Siegismund, Carsten Münk, Klaus Cichutek

Journal:

Year:

2010

Language:

english

File:

PDF, 1.33 MB

english, 2010

48

Escape from R-peptide deletion in a γ-retrovirus

Irene C. Schneider, Manon Eckhardt, Julia Brynza, Mary K. Collins, Klaus Cichutek, Christian J. Buchholz

Journal:

Year:

2011

Language:

english

File:

PDF, 1.23 MB

english, 2011

49

IL-2 induction by simian immunodeficiency virus involves MAP kinase signaling but is independent of calcineurin/NF-AT activity

Heide Muckenfuss, Matthias Hamdorf, Andris Avots, Ralf Sanzenbacher, Ulrich Tschulena, Klaus Cichutek, Egbert Flory

Journal:

Molecular Immunology

Year:

2006

Language:

english

File:

PDF, 414 KB

english, 2006

50

Interaction of human immunodeficiency virus type 1 Vif with APOBEC3G is not dependent on serine/threonine phosphorylation status

Kopietz, F., Jaguva Vasudevan, A. A., Kramer, M., Muckenfuss, H., Sanzenbacher, R., Cichutek, K., Flory, E., Munk, C.

Journal:

Journal of General Virology

Year:

2012

Language:

english

File:

PDF, 281 KB

english, 2012

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